Not overlooking this Friday’s game, just citing history: the region III team, Silsbee, put the hurt on region IV’s Somerset back in 2018. Things have changed since then of course.
No this year like was previously states our region plays region 4 in a semi final site to be determined. And even in previous years your seeding scenario was not true. They do seed the teams normally but take the top two seeds, determined by winning percentage, and place them opposite each other. The teams they face are by random draw of the other two. This is discussed every year, but since only the state championships are going to be in SA, at least as a part of a state tourney, its different this year.